Ke hana nei nā limahana noiʻi kaulana a puni ka uaki e hāʻawi i ke kuhikuhi pehea e mālama pono ai iā ʻoe iho inā manaʻo ʻoe ua maʻi ʻoe COVID-19 coronavirus.
Hoʻokuʻu ʻia nā noiʻi lapaʻau ʻana ma COVID-19 me ka wikiwiki loa, e ulu pinepine ana i ka huikau no nā mea maʻalahi e like me ka mea e lawe ai i nā mea ʻeha, a pehea e mālama ai i nā lālā ʻohana maʻi ma ka home.
No ke alakaʻi ʻana, huli ʻo National Geographic i nā kauka alakaʻi alakaʻi a me nā mea noiʻi ma waena o ka US a me Kanada no kā lākou mau manaʻo e pili ana i ka mālama ʻana i ka home, a me ka wā e ʻimi ai i ka lāʻau lapaʻau.
ʻEono mau kauka alakaʻi e wehewehe i ka mea a mākou e ʻike nei mālama iā COVID-19 i ka lumi pilikia a ma ka home.
Pehea e hoʻopili ai i kahi fiva
ʻO ka nūhou maikaʻi ma kahi o 80 pākēneka o nā hihia COVID-19 āpau e hōʻike wale nei i nā ʻōuli akahai a kaulua ʻole e pono ai ka haukapila. Paipai nā kauka i kēia poʻe maʻi e hoʻokaʻawale iā lākou iho, e noho hydrated, ʻai maikaʻi, a mālama i kā lākou hōʻailona e like me ka hiki iā lākou.
No ka mālama ʻana i ke kuni e pili ana i nā maʻi he nui, e like me COVID-19, ʻōlelo nā kauka e lawe i ka acetaminophen — i ʻike ʻia ma waena he paracetamol — ma mua o ka ibuprofen. Inā mau ke kuni, pono i nā mea maʻi e noʻonoʻo e hoʻololi i ka ibuprofen, i ʻōlelo ʻia ʻo Julie Autmizguine, he loea maʻi maʻi maʻi pediatric ma CHU Sainte-Justine ma Montreal, Kanada.
Hōʻike ʻo ia a me nā kauka ʻē aʻe i kēia makemake no ka mea ʻo ka ibuprofen a me nā lāʻau e pili ana - i kapa ʻia ʻo NSAID no ka pōkole - hiki ke loaʻa nā hopena ʻino no nā poʻe maʻi me COVID-19 coronavirus, e like me ka ʻeha o ka puʻuwai, nā maʻi ʻōpū o ka ʻōpū, a me ke kahe o ka gastrointestinal.
Eia naʻe, ʻaʻole kēia ʻōlelo aʻoaʻo i ka ibuprofen a me nā NSAID e hoʻomāhuahua i nā hopena me ka coronavirus, e like me nā moʻolelo nūhou viral i hōʻike ʻia i ka pule i hala ma hope o ka ʻōlelo ʻana a ke Kuhina Ola o Palani e pono e hōʻalo ʻia nā lāʻau i ka wā o ka COVID-19 therapy.
"ʻAʻole au i ʻike ua hōʻike ʻia nā NSAID he pilikia maikaʻi ʻole no kēia maʻi a no kekahi coronavirus paha," i ʻōlelo ʻia e ka loea ʻo coronavirus ʻo Stanley Perlman, he pediatrician a me kahi immunologist ma ke Kulanui ʻo Medicine o ke Kulanui o Iowa.
Hele pū mai ka Acetaminophen me nā mea weliweli, a lawe wale ka poʻe iā ia inā ʻaʻohe maʻi āpau a ʻaʻohe o lākou ʻeha o ke ake. Palekana ʻo ka lāʻau i nā koina o kēlā me kēia lā o ka emi o 3,000 milligrams, akā ʻo ka ʻoi aku o kēia kiʻekiʻe o kēlā me kēia lā hiki ke ʻaʻa i ka ʻeha o ke ake a ʻoi paha ka maikaʻi.
"ʻO ka overdose Acetaminophen ke kumu maʻamau o ke kūpikipiki ʻole o ke akepaʻa maʻAmelika Hui Pū ʻIa," wahi a José Manautou, kahi lāʻau ʻona ma ke Kula ʻo Pharmacy o ke Kulanui o Connecticut.
Pono e ʻike ka poʻe no ka mālama ʻana i nā lāʻau āpau a lākou e ʻai ai, ʻoiai ʻo nā lāʻau ʻoi loa e kuhikuhi i nā hōʻailona flu a me kekahi mau mea kōkua hiamoe e loaʻa pinepine i ka acetaminophen. Pono nō hoʻi ka poʻe e hōʻalo i ka inu waiʻona ke lawe i ka acetaminophen. Hilinaʻi ke akepaʻa i ka mea like — glutathione — e hoʻonāukiuki i ka hiki ke loaʻa o ka waiʻona a me ka acetaminophen. Inā ʻoe e ʻai nui i nā mea ʻelua, hiki iā ia ke hōʻiliʻili i nā toxins i loko o ke kino. (I ka manawa e maʻi ai kou kino, ʻo kēia ka hana a ka coronavirus.)
He aha e pili ana iā CHLOROQUINE a me AZithROMYCIN?
Ke hana nei nā hui olakino nonstopop e aʻo pehea e mālama pono ai iā COVID-19, a i loko o ka pule i hala aku nei, ua hui pū ka Pelekikena US ʻo Donald Trump i ka hakakā ma o ka leo ʻana i kāna kākoʻo no ʻelua mau lāʻau i hala i mau makahiki he nui — ka azithromycin antibiotic, a me kahi mana o ka lāʻau antimalarial chloroquine.
I ka ʻoiaʻiʻo, ʻaʻole i ʻae ka US Food and Drug Administration i ka hydroxychloroquine - hoʻohana pinepine ʻia e mālama i ka rheumatoid arthritis a me lupus - no ka hoʻohana ʻana me COVID-19, ʻoiai ua ʻae ʻia kahi hoʻokolohua me ka azithromycin i hāʻawi ʻia no New York. I kēia manawa, ke koi nei nā luna olakino a puni ka honua, ʻo Anthony Fauci, ke poʻo o ka US National Institute of Allergy and Infectious Diseases, e akahele e pili ana i nā lāʻau.
"ʻO ka nui o nā mea āu e lohe ai ma laila ka mea aʻu i kapa aku ai he hōʻike anecdotal," i ʻōlelo ʻo Fauci i loko o kahi hālāwai ninaninau i ka Pōʻaono no ka White House coronavirus task force. "ʻO kaʻu hana ka hōʻoia hope loa me ka ʻole o ka kānalua ʻole ka palekana o ka lāʻau, akā holo maoli nō ia."
Ua hoʻomaka ka moʻolelo chloroquine me kekahi mau haʻawina liʻiliʻi mai Kina a me Palani-he mau hemahema kā lāua a hāʻawi i kekahi mau haʻawina no nā mea maʻi i ka nui. Hoʻokumu ʻia nā hopena Palani ma ka 36 mau kānaka wale nō a kau i ka maʻi viral o nā mea maʻi, a i ʻole ka nui o nā maʻi i loko o ke kino. ʻOiaʻiʻo, ʻo nā mea maʻi wale nō e make a i ʻole e hoʻouna ʻia i ka mālama nui ʻana i ka noiʻi Farani i lawe i ka hydroxychloroquine.
"ʻAʻohe o mākou ʻikepili mai nā hoʻokolohua hoʻokolohua ʻole ʻia e haʻi ana iā mākou pehea ka chloroquine i hana ai i nā kānaka maoli," wahi a Annie Luetkemeyer, he loea no ka maʻi HIV a me nā maʻi maʻi lele i ke Kulanui o Kaleponi, San Francisco, Keʻena ʻOihana Lapaʻau.
ʻO ka lāʻau ponoʻī me hydroxychloroquine a me azithromycin no ka poʻe maʻi me COVID-19 coronavirus e hele pū me nā mea weliweli, no ka mea hiki i nā lāʻau ʻelua ke hoʻonāukiuki i ka puʻuwai a hoʻonui i ka makaʻu o ka arrhythmia. Ma ka Pōʻakahi, ua hoʻohiki ka pelekikena e hoʻouna i New York he mau kaukani o ka combo no ka hoʻāʻo ʻana iā FDA, ʻaʻole i liʻuliʻu ma hope ua hōʻike ʻia kahi haukapila ʻo Arizona ua make kekahi o kāna mau maʻi ma hope o ka lāʻau ponoʻī ʻana i ka chloroquine phosphate, kahi ʻano o ka hui i hoʻohana ʻia e hoʻomaʻemaʻe i ka aquarium. pahu poʻomanaʻo. Ua hōʻike nā luna olakino Nīlani i ʻelua mau hihia o ka chloroquine overdosis i ka hopena pule.
"ʻO ka mea hope loa a mākou e makemake ai i kēia manawa, ʻo ia ka hoʻonui ʻana i kā mākou keʻena kūpilikiʻi me nā mea maʻi i manaʻoʻiʻo ua loaʻa iā lākou kahi hopena maikaʻi ʻole a weliweli hoʻi e hiki ai ke hōʻoweliweli i ko lākou olakino," ʻo Daniel Brooks, ke alakaʻi olakino o ka Banner Poison a me ka ʻOihana ʻIke ʻIlikino lāʻau ma Phoenix , wahi a kahi ʻōlelo.
PAKELE ANEI NA LAAU KUMU O KE KOKO?
ʻO nā mea kāohi ACE, nā lāʻau i hoʻohana ākea e mālama i ke koko kiʻekiʻe, ua hele pū kekahi i lalo o ke ahi i ka wā o ka pilikia COVID-19, me kekahi mau hōʻike e hōʻike ana e pono i nā mea maʻi ke hoʻopau i ka lawe ʻana i kēia mau lāʻau inā ulu lākou i nā ʻōuli.
I loko o kahi mau leka i loko o ka British Medical Journal, Nā Manaʻo Kūlohelohe Cardiology, a me The Lancet Respiratory Medicine, ua hāpai nā mea noiʻi i nā nīnau inā paha e kōkua nā mea kāohi ACE i nā maʻi coronavirus i loko o nā māmā o ka poʻe. Hoʻokumu ka hopohopo no ka mea ʻo SARS a me ka coronavirus hou e komo i nā hunaola ma ke kau ʻana i kahi protein i kapa ʻia ʻo ka angiotensin-hoʻololi i ka enzyme 2, a i ʻole ACE2 no ka pōkole. Hoʻonui ka protein i nā papa o nā hunaola i ka puʻuwai a me nā māmā, kahi e kōkua ai i ka hoʻoponopono ʻana i kahi hōmona e pili ana i ke kaomi ʻana o ke koko.
ʻO kekahi hopena o nā mea kāohi ACE hiki iā lākou ke hoʻoulu i nā hunaola e hoʻonui i ka ACE2. Ua loaʻa kahi noiʻi ma 2005 i kahi hōʻike o ka piʻi ʻana o nāʻiole, a ua ʻike ʻia kahi noiʻi ma 2015 i nā kānaka i hoʻonui ʻia nā pae ACE2 i ka mimi o nā maʻi e lawe ana i ka lāʻau e pili ana i nā mea kāohi ACE.
Akā ʻaʻohe hōʻike i kēia manawa e hōʻino ana nā mea kāohi ACE i nā hopena COVID-19 i loko o ke kanaka, e like me ka American Heart Association, ka European Society of Cardiology's Council on Hypertension, a me kahi hōʻike 20 Malaki i paʻi ʻia ma ka European Heart Journal. ʻO nā ʻōlelo aʻoaʻo ʻoi loa a nā kauka inā ʻoe i kuhikuhi ʻia i kahi lāʻau, hoʻomau i ka lawe ʻana a haʻi ʻia e kāu kauka.
"ʻAʻole pono mākou e hoʻomaka a kū ʻole paha i kēia mau lāʻau a hiki i ka loaʻa ʻana o ka ʻike hou aku," wahi a Luetkemeyer.
ʻO ka poʻe me ke koko kiʻekiʻe a me nā maʻi puʻuwai e ʻike ʻia ma kahi kiʻekiʻe o ka makaʻu no COVID-19, akā ʻoi aku paha ka mea e pili ana i nā maʻi kūlohelohe iā lākou iho. He aha hou aʻe, he waiwai anti-inflammatory paha nā mea kāohi ACE, kahi e kōkua ai i nā ake māmā o nā maʻi COVID-19 e kū maikaʻi me ka maʻi. (E aʻo pehea e hoʻonui ai ke koʻikoʻi o ka coronavirus i kēia mau kumu.)
"He haʻawina nui kēlā, e hoʻohālikelike i ka poʻe me ke koko kiʻekiʻe a hoʻēmi paha i kēia mau lāʻau, e ʻike ai inā aia he ʻokoʻa," wahi a Perlman. "Akā paʻakikī e hana, a paʻakikī paha e hoʻāpono i ke ʻano."
I ka manawa e ʻimi ai i ka noʻonoʻo kino
"Ma nā ʻano āpau, inā loaʻa ʻoe i nā ʻōuli hanu ulia pōpilikia a i ʻole mea e pilikia ai kekahi mea, makemake mākou e ʻimi ʻoe i ka ulia pōpilikia," i ʻōlelo ʻo Purvi Parikh, he loea a me ka loea o ka maʻi maʻi lele ma NYU Langone ma New York City. Inā koho ʻoe e ʻimi i ke kōkua ma kahi haukapila kūloko, eia kahi laʻana o ka mea āu e manaʻo ai.
Ma ka haukapila hae Inova Health System ma Fairfax, Virginia, ua kūkulu nā limahana i hale lole i waho e hoʻokaʻawale i ka poʻe e hōʻike nei i nā maʻi hanu mai nā poʻe me nā maʻi ʻē aʻe. Hoʻonohonoho ʻia nā hui ʻelua i nā ʻāpana like ʻole o ke keʻena kali, hoʻokaʻawale ʻia e ʻeono mau kapuaʻi o ke akea.
Ma muli o ka hemahema o nā hoʻokolohua ma o ka US, ua ʻōlelo nā kauka ma Inova a me nā haukapila ʻē aʻe inā hele mai ka poʻe me nā ʻōuli palupalu, ʻōlelo ʻia kēia mau maʻi e loaʻa iā lākou ʻo COVID-19 a paipai ʻia lākou e quarantine ponoʻī e pale i ka hoʻonui nui ʻana i ka 920,000 o ka lāhui. moena limahana.
No ka poʻe maʻi me ka COVID-19 coronavirus a ke hōʻea nei lākou me nā ʻōuli koʻikoʻi e like me ka paʻakikī o ka hanu ʻana, hoʻomaka nā limahana olakino e ka nānā ʻana i nā pae oxygen o ka mea maʻi, kaomi koko, a me ka nui o ka wai i loko o kā lākou mau māmā. mālama i ko lākou kūlana paʻa. Hoʻāʻo nō lākou e mālama i ka fiva, kahi e hiki ai ke hōʻoluʻolu a alakaʻi i ka hōʻino ʻana o ka cell.
ʻO nā hihia ʻoi loa loa o COVID-19 koi i ke kau ʻana i ka mea maʻi ma ka ʻenekini mīkini — kahi mea e pōʻaiapuni i ka ea i loko a i waho o nā māmā o ke kanaka — no hoʻokahi pule i hoʻokahi pule. ʻO ia ke kumu e hopohopo nui ai nā luna olakino e pili ana i ka loaʻa ʻole o ka ventilator. Wahi a ka Society of Critical Care Medicine e hiki aku ana i 200,000 ventilators i nā haukapila US, akā ua ʻoi aku ka ʻelemakule a ʻaʻole paha e mālama pono iā COVID-19. I kēia manawa, hōʻike kahi kuhi paʻakikī e ʻoi aku ma mua o 900,000 ʻAmelika i hiki ke loaʻa iā COVID-19 a pono i kahi ea.
ʻO nā hihia ʻoi loa o COVID-19 hiki ke hopena i ka mea i kapa ʻia ʻo ka maʻi hanu respiratory respiratory (ARDS), kahi ʻeha nui o ka māmā i hiki i nā ʻano maʻi ʻino ʻino. Ua wehewehe maikaʻi ʻia nā haukapila no ka lawelawe ʻana i ka ARDS. Pono e kau i nā mea maʻi ma ko lākou ʻōpū e hoʻomaikaʻi i ka hiki i nā māmā ke ea, a ʻaʻole e hāʻawi ʻia i nā wai he nui. Hoʻohui ʻia, pono e hoʻonohonoho i nā ʻenekini maʻi ARDS e hoʻoliʻiliʻi i nā lewa haʻahaʻa o ka lewa, e hoʻoliʻiliʻi i ke koʻikoʻi ma ke alveoli, nā subchambers liʻiliʻi o nā māmā.
Ma loko o nā lumi o ka haukapila, mālama nā limahana i ka hoʻohaʻahaʻa ʻana i ka hoʻohana o nā pono hana e hoʻokuʻu ai i nā droplets hanu, e like me nā mea kākoʻo oxygen e hoʻokuʻi i ka ea i loko o nā akemāmā. Ke hoʻohana akahele nei nā haukapila me ka akahele me nā pono i kapa ʻia he nebulizers, kahi e hoʻolilo ai i nā lāʻau i wai i mau ohu hanu, no ka mea hiki i nā ʻūlū ke kau iā SARS-CoV-2 ma luna. (Eia ke kumu e ʻoi aku ai ke kopa e hoʻomaʻemaʻe i ka hakakā ʻana me coronavirus.)
KA LAAU LOMAIKAI LOA?
Ke heihei nei nā mea noiʻi a me nā kauka a puni ka honua e hoʻāʻo kūpono inā paha e kope ʻia nā lāʻau like ʻole i ke kaua me COVID-19. ʻO nā kauka i nīnauele ʻia e National Geographic ua hōʻike i ka manaolana nui loa ma luna o remdesivir, kahi lāʻau antiviral e hoʻomohala ʻia e nā ʻepekema ʻo Gileada.
"ʻO ka mea wale nō aʻu e kau ai i koʻu pāpale he remdesivir," wahi a Perlman.
Hana ʻo Remdesivir ma ka mimicking ʻana i kahi palaka o RNA viral, ke kāohi nei i ka hiki ʻana o ka virus ke hoʻonui. ʻO kahi noiʻi Kina i hōʻike ākea ʻia, i paʻi ʻia ma Pepeluali 4 ma Cell Research, ua hōʻike ʻia ua hoʻopau ʻo remdesivir i ka hana kope ʻana o ka SARS-CoV-2 i loko o ka hale hōʻikeʻike. Akā he hoʻokolohua nō ia o ka lāʻau a ua ʻike i nā hemahema i ka wā i hala. Ua hoʻomohala mua ʻia ʻo Remdesivir e kaua aku iā Ebola, akā ua kūleʻa ʻole kāna mau hoʻokolohua hoʻokolohua i nā kānaka.
Nānā ʻole, ʻo ka loaʻa ʻana o kahi lāʻau kūpono e koi ikaika ʻia ai nā hoʻokolohua hoʻokolohua kanaka, kahi e lawe ai i kahi manawa e alakaʻi ai. "I ka nānā ʻana i mua, maikaʻi inā inā mākou e hoʻokomo i nā hana hou aku i nā lāʻau anti-coronavirus," hoʻohui ʻo Perlman. "Maʻalahi e ʻōlelo i kēia manawa, [akā] ʻelima mau mahina i hala, ʻaʻole maʻalahi."
