Nuhou Uea

Ala Hou e pale aku ai i ka ma'i ma'i mai ka Halemai me ka Pum

i kakauia ma hoʻoponopono

Ma ka hōʻike ʻana i ke ʻano o kahi protein i hoʻohana ʻia e ka bacteria e puhi i nā lāʻau lapaʻau, ua hoʻolālā kahi hui noiʻi i kahi lāʻau lapaʻau mua e sabotage i ka pama a hoʻihoʻi i ka pono o nā lāʻau antibiotic.        

Alakaʻi ʻia e nā mea noiʻi mai ke Kulanui o New York, NYU Grossman School of Medicine, a me NYU Langone's Laura a me Isaac Perlmutter Cancer Center, ua hoʻohana ka noiʻi hou i ka microscopy kiʻekiʻe e "ʻike" no ka manawa mua i ke ʻano o NorA, kahi protein i loaʻa i ka ʻano bacteria Staphylococcus. hoʻohana ʻo aureus i nā lāʻau antibiotic i hoʻohana nui ʻia ma mua o ka hiki ke pepehi iā lākou.

Hōʻike nā pāpaʻi Efflux i hoʻokahi ʻano hana a S. aureus i hoʻomohala ai i ke kū'ē i nā fluoroquinolones, he hui o nā lāʻau ʻokoʻa ʻoi aku ma mua o 60 i ʻae ʻia e komo pū me norfloxacin (Noroxin), levofloxacin (Levaquin), a me ciprofloxacin (Cipro). ʻAʻole pono nā Fluoroquinolones i kēia manawa i kekahi mau maʻi bacterial kū'ē i ka lāʻau, e like me ka methicillin-resistance S. aureus (MRSA), kahi kumu nui o ka make ma waena o nā maʻi maʻi i ka wā e paʻakikī ai nā maʻi, wahi a nā mea noiʻi. No kēia kumu, ua ʻimi ka māla i ka hoʻolālā ʻana i nā mea hoʻopiʻi efflux pump, akā ua pale ʻia nā hoʻāʻo mua e nā hopena ʻaoʻao.

"Ma mua o ka hoʻāʻo ʻana e ʻimi i kahi lāʻau antibiotic hou, ke manaʻo nei mākou e hana i nā lāʻau ʻokoʻa i hoʻohana nui ʻia i nā makahiki i hala aku nei, i hoʻohana ʻole ʻia e ka pale ʻana i ka maʻi bacteria, ʻoi aku ka maikaʻi," wahi a ka mea kākau noiʻi mua ʻo Doug Brawley, PhD. Ua hoʻopau ʻo ia i kāna ʻatikala kauka i loko o nā hale hana o nā mea kākau kiʻekiʻe ʻo Nate Traaseth, PhD, he polopeka ma ke Keʻena ʻOihana Kimia ma ke Kulanui o New York, a ʻo Da-Neng Wang, PhD, he kumu aʻoaʻo ma ke Keʻena o Cell Biology ma NYU Grossman School of Medicine. .

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