ʻO ka hoʻohana hou ʻana o Sputnik Light Vaccine ma ke ʻano he Universal Booster

Aia he 2 biliona poʻe i loaʻa i nā lāʻau lapaʻau Kina inactivated ma ka ʻāina a me ka honua. ʻOiai ua ʻae ʻo Kina i ka hui ʻana a me ka hoʻoikaika ʻana i ka hoʻoulu ʻana me nā kano o ka home, hiki i ka Russian one-shot Sputnik Light vaccine ke lilo i mea hoʻoikaika honua no ka poʻe i hoʻopaʻa ʻia me nā kano Kina ma nā ʻāina ʻē aʻe o ka honua e hoʻoikaika a hoʻolōʻihi i ko lākou pale ʻana mai COVID.

Ua ʻae nā luna hoʻoponopono o Kina i ka hui ʻana o nā kano i hana ʻole ʻia e kūʻē iā COVID (ʻo ia hoʻi, ʻo Sinovac a me Sinopharm) a me ka hoʻohana ʻana i kahi kano ʻokoʻa, me ka adenoviral-based, e like me ka booster shot e hāʻawi hou ana i kahi hōʻoia hou o ka pono o ka mix & match approach i paionia. e ka Russian Sputnik V vaccine i ka hana ʻana i ka pale ʻoi aku ka ikaika a me ka lōʻihi, me ka kūʻē i ka ʻano Omicron.

Hoʻohana nui ʻia nā lāʻau lapaʻau i hana ʻia e nā hui Kina (Sinovac a me Sinopharm) me ka ʻoi aku o 4.7 biliona doses i hoʻolako ʻia ma Kina a me ka honua. ʻOiai ua ʻae ka ʻAha Mokuʻāina ʻo Kina i ka hui ʻana a me ka hoʻoikaika ʻana i ka hoʻoulu ʻana me nā lāʻau lapaʻau home wale nō [1], hiki i ka Russian one-shot Sputnik Light vaccine (ka mea mua o Sputnik V) hiki ke lilo i mea hoʻonā no ka hoʻonui ʻana i ka poʻe i hoʻopaʻa mua ʻia me nā kano Kina ma nā ʻāina ʻē aʻe a puni. ka honua.

Ua hōʻike mua ʻia ʻo Sputnik Light i nā hopena ikaika i hoʻohana ʻia ma ke ʻano he mea hoʻoikaika i nā hoʻāʻo ʻana a me nā hoʻāʻo ʻana, e komo pū ana no nā kano i hana ʻole ʻia. No ka laʻana, ʻo ke aʻo ʻana i hana ʻia ma Argentina ma ka hui pū ʻana o Sputnik Light me nā lāʻau lapaʻau ʻē aʻe ua hōʻike ʻia ka pane ʻana o ka antibody a me nā T-cells i hāpai ʻia e Sputnik Light ma ke ʻano he mea hoʻoikaika i ka maʻi maʻi Sinopharm inactivated he 10x kiʻekiʻe ma mua o ʻelua mau pana o Sinopharm. Ua hōʻike pū ʻia ka haʻawina ʻo kēlā me kēia hui "vaccine cocktail" me Sputnik Light me nā lāʻau lapaʻau ʻē aʻe e like me Moderna, AstraZeneca a me Cansino i hāʻawi i kahi titer antibody kiʻekiʻe ma ka lā 14 ma hope o ka hoʻokō ʻana i kahi maʻi lua ke hoʻohālikelike ʻia me ka homologous mua (ʻo ka lāʻau lapaʻau like me ka mua a ka lua o ka nui) regimens o kela a me keia o na kano. ʻO ka hoʻohana ʻana i ka Sputnik Light i hui pū ʻia me nā lāʻau lapaʻau ʻē aʻe a pau i hōʻike i ka ʻike palekana kiʻekiʻe me ka loaʻa ʻole o nā hopena koʻikoʻi ma hope o ka hoʻopaʻa ʻana i nā hui.      

ʻO ke ala hoʻoikaika heterogeneous ("vaccine cocktail" me ka hoʻohana ʻana i ke kanaka adenovirus serotype 26 ma ke ʻano he ʻāpana mua a me ke kanaka adenovirus serotype 5 ma ke ʻano ʻelua) i paionia e ka Russian Gamaleya Center ma ke kumu o Sputnik V, ka lāʻau lapaʻau mua i hoʻopaʻa ʻia ma ka honua e kūʻē i ka coronavirus. Ua hōʻike ʻia kēia ala i ka kūleʻa i ka hana ʻana i ka pale ʻana i ka coronavirus e like me ka hōʻike ʻana e ka ʻikepili maoli mai Hungary, San Marino, Argentina, Serbia, Bahrain, Mexico, UAE a me nā ʻāina ʻē aʻe.

I kēia lā, ua ʻae ʻia ʻo Sputnik Light ma nā ʻāina ʻoi aku ma mua o 30 me ka nui o ka heluna kanaka ma luna o 2.5 biliona a me Sputnik V - ma nā ʻāina 71 me ka heluna kanaka ma mua o 4 billion mau kānaka.

Hoʻokumu ʻo Sputnik V i ka pane ʻoi aku ka ikaika a ʻoi aku ka lōʻihi e kūʻē iā COVID (me ka ʻano ʻano Omicron) ma mua o nā kano ʻē aʻe, i hoʻoikaika ʻia e ka Sputnik Light booster. ʻO kahi noiʻi hoʻohālikelike kūʻokoʻa [3] i mālama ʻia ma Lazzaro Spallanzani National Institute for Infectious Diseases ma Italia e kahi hui o 12 Italia a me 9 mau ʻepekema Lūkini i alakaʻi ʻia e Francesco Vaia, Luna Hoʻokele o ka Spallanzani Institute a me Alexander Gintsburg, Luna Hoʻokele o ka Gamaleya Center i hōʻike i kēlā. Hōʻike ka lāʻau lapaʻau Sputnik V ma mua o 2 mau manawa kiʻekiʻe o ka nui o ka maʻi neutralizing antibodies i ka Omicron (B.1.1.529) ʻokoʻa ma mua o 2 mau puʻupuʻu Pfizer (2.1 mau manawa kiʻekiʻe ma ka huina a he 2.6 manawa kiʻekiʻe 3 mau mahina ma hope o ka hoʻopaʻa ʻana).

Ua mālama ʻia ke aʻo ʻana ma nā kūlana hoʻokolohua like i nā laʻana sera like ʻole mai nā poʻe i hoʻopaʻa ʻia me Sputnik V a me Pfizer me kahi pae like o nā antibodies IgG a me ka hana hoʻomaʻamaʻa virus neutralizing (VNA) kūʻē i ka ʻano ʻano Wuhan. Ua hōʻike ʻo Sputnik V i ka liʻiliʻi liʻiliʻi (2.6 mau manawa) i ka hana hoʻomaʻamaʻa ʻana i ka maʻi virus e kūʻē iā Omicron i ka hoʻohālikelike ʻana i ka ʻano ʻokoʻa ʻo Wuhan ma mua o ka maʻi Pfizer (8.1-paʻi hōʻemi no Sputnik V ma ke ʻano he 21.4-paʻi hoʻemi no ka maʻi Pfizer).